盐酸普鲁卡因水解反应研究  

Study of the Hydrolytic Reaction of Procaine Hydrochloride in Aqueous Solution

作　　者：张新民[1] 王俊卿[1] 谢鋆[1] 杨利红[1] 

机构地区：[1]兰州医学院药学系分析物化教研室

出　　处：《兰州医学院学报》1993年第2期82-85,共4页Journal of Lanzhou Medical College

摘　　要：本文用恒温动力学方法研究盐酸普鲁卡因的水解反应。用双波长分光光度法测定了水解过程中盐酸普鲁卡因的浓度,观察了PH值(1.96～8.99)和温度(60℃～120℃)对此反应的影响,并得出其稳定性预测结果。In this paper the hydrolysis of procaine hydrochloride in aqueous solution has been studied by the isothermal kinetics method. The concentration of procaine hydrochloride in aqueous solution is determined by the dual wavelength spectrophotometry. The hydrolytic rate is dependent on PH(1.96～8.99) and temperature (60℃～120℃) has been investigated. The experimental result of the stability of procaine hydrochloride in aqueous solution has been showed.

关 键 词：盐酸 普鲁卡因 水解反应 稳定性 

分 类 号：R727.11[医药卫生—儿科]