清凉活血饮治疗血热瘀阻型视网膜静脉阻塞68例临床研究  

Clinical Study on Qingliang Huoxue Yin for Treatment of 68 Cases of Retinal Vein Obstruction of Blood Heat Stagnation Type

作　　者：王彤云[1] 洪宜成[1] 陈若霞[1] 钱朋寿[1] 王贤勤[1] 

机构地区：[1]南京市中医院眼科中心检验科,江苏省南京市金陵路1号210001

出　　处：《中医杂志》2004年第10期757-759,共3页Journal of Traditional Chinese Medicine

摘　　要：目的:观察清凉活血饮治疗血热瘀阻型视网膜静脉阻塞(RVO)的疗效及作用机理。方法:对眼底荧光血管造影(FFA)确诊为RVO的患者进行中医辨证,将血热瘀阻型患者随机分为两组,治疗组68例给予自拟清凉活血饮口服,对照组30例给予脉络宁静脉滴注,观察两组的临床疗效及治疗组治疗前后血液流变学、血浆组织型纤溶酶原激活剂(T-PA)和纤溶酶原激活剂抑制物(PAI)活性的变化。结果:治疗组总有效率为80.9%,优于对照组(P<0.05)。治疗组治疗后血液流变学明显改善,血浆T-PA明显上升,PAI明显下降,明显优于治疗前(P<0.01)。结论:清凉活血饮具有降低血液粘稠度、调节机体纤溶系统功能的作用,治疗血热瘀阻型RVO效果较好。Objective: To observe therapeutic effect of Qingliang Huoxue Yin on retinal vein obstruction(RVO) of blood heat stagnation type. Methods: The patients of RVO were definitely diagnosed by fundus fluorescein angiography(FFA). Among them, the patients of blood heat stagnation type were randomly divided into a treatment group(n=68) treated by self-stipulated Qingliang Huoxue Yin and a control group(n=30) treated by intravenous drip of Mailuoning. Clinical therapeutic effects of the two groups and changes of hemorhologic indexes, and plasma tissue type plasminogen activator (T-PA) and plasminogen activator inhibitor(PAl) activities after treatment in the treatment group were investigated. Results: The total effective rate was 80.9% in the treatment group. superior to the control group (P<0.05), and after treatment the hemorhelogic indexes improved and plasma T-PA increased and PAI decreased significantly in the treatment group, superior to that before treatment (P<0.01). Conclusion: Qingliang Huoxue Yin has a better therapeutic effects for the patient of RVO of blood heat stagnation type.

关 键 词：治疗组 血热 热瘀 活血 RVO 视网膜静脉阻塞 对照组 结论 上升 目的 

分 类 号：R276.7[医药卫生—中医五官科学]