宁心红杞胶囊对围绝经期综合征的治疗作用  

Clinical Effect of Menoprogen on Menopausal Syndrome

作　　者：韦镕澄[1] 徐昌芬[2] 马红[3] 郑真[4] 刘万菊[4] 吕晔[5] 

机构地区：[1]南京医科大学二附院,江苏南京210029 [2]南京医科大学生殖医学中心,江苏南京210029 [3]南京中医药大学附院,江苏南京210029 [4]解放军第454医院,江苏南京210002 [5]江苏省中科院植物研究所,江苏南京210014

出　　处：《药学进展》2004年第11期521-523,共3页Progress in Pharmaceutical Sciences

摘　　要：目的 :观察长期服用纯中药制剂宁心红杞胶囊 ,对围绝经期妇女症状、子宫内膜、性激素水平的影响。方法 :绝经未逾 5年妇女 2 6例 ,未绝经妇女 14例 ,持续服用宁心红杞胶囊 3个月以上 ,观察其临床症状、阴道脱落细胞、血清中女性激素含量、阴道流血及子宫内膜厚度等的变化。结果 :长期服药后 ,临床症状好转 ,阴道脱落细胞伊红指数上升 ,女性激素稳定在一定水平 ,无阴道不规则流血现象 ,子宫内膜增值在正常范围内。结论 :纯中药制剂宁心红杞胶囊治疗围绝经期综合征疗效确切且安全。Objective: To assess the lo ng -term effects of Menoprogen formulated with natural herbal components without p hytoestrogens on the menopausal symptoms, endometrium and sexual hormonal level. Methods: 26 menopausal women (<5 years post menopause) and 14 perimenopausal women received Menoprogen for more than 3 months. The effects on menopausal symptoms, the eosinophilic index, serum female hormonal level, endom etrial thickness and vaginal bleeding were clinically measured. Results: The menopausal symptoms were significantly improved. The eosinophilic i ndex was increased. The female hormonal level was improved better. No significa nt endometrial hyperplasia was found. No vaginal bleeding event was reported. Menoprogen was well tolerated. Conclusion: Menoprogen has been s hown to be effective and safe in the treatment of menopausal syndromes. [

关 键 词：宁心红杞胶囊 围绝经期综合征 治疗 激素替代疗法 阴道脱落细胞 

分 类 号：R271.9[医药卫生—中西医结合]