SARS患者康复期股骨头缺血性坏死的巢式病例对照研究  

Nested case-control study of avascular necrosis of femoral head during SARS patients′ convalescence

作　　者：高宏生[1] 王世鑫[2] 曹霞[2] 惠武利[1] 李玉明[2] 杨震[2] 苏彬[2] 

机构地区：[1]武警医学院流行病学教研室 [2]武警医学院附属医院,天津300162

出　　处：《武警医学院学报》2005年第1期11-13,共3页Acta Academiae Medicinae CPAPF

摘　　要：【目的】探讨SARS患者康复期股骨头缺血性坏死的影响因素。【方法】利用病历资料调查患者治疗期间的激素用法 ,应用磁共振 (MRI)测定股骨头缺血性坏死 ,统计分析采用逐步Logistic多元回归法。 【结果】激素总量、冲击疗法和年龄在股骨头坏死因素分析中均有统计学意义 ,而SARS病毒血清抗体无统计学意义。【结论】股骨头缺血性坏死主要与治疗期间激素总量、冲击疗法和年龄有关 ,SARS病毒对股骨头缺血性坏死可能没有作用。To explore the factors affecting the avascular necrosis of femoral head during S ARS patients′ convalescence. The usage of corticosteroids in SARS patients′ therapy w as reviewed with case history. The avascular necrosis of femoral head were measu red with MRI(magnetic resonance imaging). The factors of femoral necrosis included the age, the dos age summation of corticosteroids and implosion therapy. There were no relations between the serum antibody IgG and the avascular necrosis of femoral head of the SARS patients in statistics.[Conclusion]The occurance of avascular necrosis of femoral head is well related with the age, the dosage sum and implosion therapy of corticostero ids. The symptom what is avascular necrosis of femoral head couldn′t be affecte d by the SARS virus.

关 键 词：SARS 糖皮质激素 股骨头 

分 类 号：R681.2[医药卫生—骨科学]