肝豆状核变性脾切除的探讨——(附42例报告)  

Splenectomy in patients with hepatolenticular degeneration

作　　者：蔡永亮[1] 杨兴涛[1] 杨任民[1] 

机构地区：[1]安徽中医学院附属医院,230031

出　　处：《临床神经病学杂志》1993年第3期131-133,共3页Journal of Clinical Neurology

摘　　要：肝豆状核变性(HLD)并发脾功能亢进患者,于脾切除或/及分流术后极易招致神经症状迅速恶化而死亡,故长期以来大多数学者不主张手术。作者等对42例并发脾亢的HLD患者,于手术前采用中西医结合驱铜治疗,结果38例术后血细胞显著增高而神经症状基本未加重,术后死亡4例均为28岁以上的脑-肝型患者。Clinical deterioration or death often occurs in HLD patients with hypersplenia following splenectomy or/and shunt. Thus it is long believed that splenectomy and shunt are unfit for HLD patients complicated With hypersplenia. Because hypersplenia can reduce immune ability, deficient hemopoiesis make long-term therapy difficult, and because bleeding oesophageal varices is usually lifethreatening, we treated 42 HLD patients with hypersplenia by copper-excreting therapy before operation. Our results showed that although clinical symptoms in 38 patients were apparently unchanged, however blood cells were increased significiently after Operation. Only 4 patients with brain-liver type died.

关 键 词：肝豆状核变性 脾功能亢进 脾切除 

分 类 号：R657.6[医药卫生—外科学]