城镇人群1194例HP尿素酶抗体测定对HP流行病学的研究  

Seroepidemiological Study of Helicobacter Pylori in 1194 Cases of Cities and Towns Detecting Anti--urease Antibody

作　　者：李智[1] 陈振侬[1] 洪瑞香[1] 

机构地区：[1]广西医科大学附属一院消化科,研究生桂林医学院工作530027

出　　处：《临床消化病杂志》1993年第2期49-51,共3页Chinese Journal of Clinical Gastroenterology

摘　　要：以6株幽门螺杆菌(HP)尿素酶作为抗原,用间接酶联免疫法(ELISA)检测城镇人群1194例HP感染的流行病学调查。结果:该试验敏感性为90％,特异性为90％;HP感染率为40.2％,并随年龄增长而增加;有上消化道症状的HP感染率明显高于无症状者(P<0.05)。其感染率与性别、职业、地区分布、血型和个人烟酒嗜好无关。The urease extract of Helicobacter pylori (HP) was used as antigen to detect sera anti-urease antibodies of HP in 1194 cases of cities and towns by ELISA for the epidemiological study of HP infection. The results showed that sensitivity and specificity were 90% respectively, the HP infection rate was 40.2% and was increased with age and was higher (P<0.05) among persons with upper gastrointestinal symp- toms than without those symptoms. HP infection had no relation to sexes, occupation, blood types, regions, smoking and drinking.

关 键 词：幽门螺杆菌 流行病学 尿素酶 抗体 

分 类 号：R378.2[医药卫生—病原生物学]