风湿性二尖瓣病变患者运动心肺功能测定  

Cardiopulmonary exercise testing in rheumatic mitral valve disease (RMVD)

作　　者：黄思贤[1] 谭新洪[1] 陈传荣[2] 邓法权[2] 彭锦泉[1] 李明耻[1] 鲁小燕[1] 

机构地区：[1]广东省人民医院内科,510080 [2]广东省心血管病研究所

出　　处：《临床心血管病杂志》1993年第3期147-151,共5页Journal of Clinical Cardiology

摘　　要：对23例女性RMVD患者进行踏车负荷递增试验,并以10例正常女性作对照。结果发现RMVD组最大运动受限于下列心脏因素:最大有氧代谢能力VO_2max/kg,无氧阈VO_2AT/kg、VO_2AT/VO_2max pred及氧脉搏(VO_2/HR)max明显减低。而VO_2AT/VO_2max则高于对照组。表明RMVD组AT出现较早,且不能耐受无氧代谢而终止运动。此外HR-VO_2/kg图示低氧耗高心率。VO_2/HR-VO_2/kg曲线趋于低平。有氧代谢能力减损FAI增高。呼吸储备正常,呼吸困难指数Dl在50％时,已由上述心脏因素而终止运动。Using bicycle ergometer, incremental exercise testing were performed in twenty three female patients with RMVD and compared with ten female normal subjects. In RMVD group, maxium exercise was limited by following cardiac factors; maximal aerobic capacity (VO2 max/kg), anaerobic threshold(AT)(VO2AT/kg, VO2AT/VO2max pred),and O2pulse max(VO2/HR max), they were significantly lower in RMVD group thencontrol group. But VO2AT/VO2max was higher. It revealed that AT occured earlier in RMVD group and the patiercs could not tolerated too much time for anaerobic metabolismand then stoped exercise after AT being reached. Ralating to HR, VO2/kg became more steep in RMVD group, that indicated lower oxygen uptake and higher heart rate. AlsoO2pulse-VO2/kg relationship during incremental exercise showed that O2pulse slope in RMVD group was more flatter, and functional aerobic impairment (FAI) increased in RMVD group. When Dyspnea index (DI) was arrived at 50% the patients had to end the exercise testing due to above cardiae factors, that revealed the patients had a normal breathing reserve.

关 键 词：二尖瓣病变 心脏功能试验 

分 类 号：R542.510.4[医药卫生—心血管疾病]