再生障碍性贫血患者切脾治疗前后的红细胞寿命的观察  

Observation of Therapeutic of Splenectomy of Erythrocyte Life Span in Aplastic Anemia

作　　者：刘访杰[1] 储榆林[1] 瞿全[1] 杨崇礼[1] 赵艳津[1] 

机构地区：[1]中国医学科学院血液学研究所,300020

出　　处：《临床血液学杂志》1993年第3期117-119,共3页Journal of Clinical Hematology

摘　　要：本文用^(51)铬标记受检者自身红细胞法,对16例健康人及7例慢性再生障碍性贫血(慢再)患者,切脾治疗前后的红细胞寿命(RBC T_(1/2))及其破坏部位的测定值进行了比较分析。6例慢再患者的SDI、S/L、SLI值高于正常值,切脾后RBC T_(1/2)延长了0.8～14.8天,切脾治疗有效。1例SDI、S/L、SLI值在正常值范围,切脾后RBC L_(1/2)无增加,切脾治疗无效。因之,RBC T_(1/2),SDI、S/L、SLI的测定对遴选切脾治疗病例及观察疗效,有一定的临床意义。This paper reports the result of a clinical study of the life span andthe site of destruction of erythrocytes of 16 normal human and 7 patients with aplasticanemia measured by ^(51)Cr labled method. 57%(4 cases) of the 7 aplastic anemia pa-tients the erythrocyte life span was shortened (<20day). The 6 cases SDI. S/L. SLI are more than the normal value. So the therapeutic of splenectomy showed is effec-tive, RBC T_(1/2) increases 0.8～14.8 date. The 1 cases SDI. S/L. SLI is in the normalrange, so the case has no effect. During the course of splenectomy therapy measuringerythrocyte life span and the site of red cells destruction has an important signifi-cance.

关 键 词：再生障碍性 贫血 红细胞 脾切除 

分 类 号：R556.5[医药卫生—血液循环系统疾病]