华山矾植物中三萜皂苷类化合物的电喷雾串联质谱研究  

作　　者：李斌[1] 再帕尔·阿不力孜[1] 唐美军[1] 浮光苗[1] 庾石山[1] 

机构地区：[1]中国医学科学院，中国协和医科大学药物研究所，北京100050

出　　处：《质谱学报》2004年第B10期35-36,共2页Journal of Chinese Mass Spectrometry Society

摘　　要：Triterpenoid saponins from Symplocos chinensis have been investigated by positive ion electrospray ionization multi-stage tandem mass spectrometry (ESI-MS^n) in a new linear ion trap mass spectrometer. It has been found that the fragmentation patterns of these given saponins significantly vary in accordance with different derivatization in the glucuronyl residue of oligosaccharide chains. The product ions show that the carboxyl group and the free hydroxyl group at the C-3' position of the glucuronyl residue are the key sites for determining the fragmentation pathways of these given triterpenoid saponins.The described results in this paper confirm the mechanisms previously postulated for cross-ring cleavage process for the metal coordinated species. Furthermore, the experimental results can benefit the determination of the minute compounds of this type in crude plant extracts and give some aid for the studies of similar glycoconjugates.

关 键 词：华山矾 三萜皂苷类化合物 电喷雾串联质谱 中草药 

分 类 号：O629.61[理学—有机化学] R284.1[理学—化学]