用多种非创伤性方法检测糖尿病病人心脏功能  

A STUDY ON CARDIAC FUNCTION IN DIABETIC PATIENTS BY MULTIPLE NON-INVASIVE METHODS

作　　者：严励[1] 陈玉驹[1] 严棠 李润南[2] 刘泽生[2] 

机构地区：[1]孙逸仙纪念医院内分泌科 [2]孙逸仙纪念医院心内科

出　　处：《中山大学学报（医学科学版）》1993年第1期52-57,共6页Journal of Sun Yat-Sen University:Medical Sciences

摘　　要：本研究对101例糖尿病病人进行多种非创伤性心功能检查。结果显示:合并高血压及/或冠心病的糖尿病人79％心功能异常,无合并冠心病,高血压及微血管病变,但合并心脏植物神经病变病人为56％,而无以上合并症的病人为47％,且心功能损害程度与微血管病变程度呈正相关。3组病人均以舒张功能损害为主,但各组病人心功能改变形式无明显不同。For the purpose of evaluating changes in cardiac structure and function in patients with diabetes mellitus, several non-invasive methods including systolic time interval, M-echocardiography and pulsed doppler echocardiography were applied in the study of 101 patients with or without complications of coronary heart disease (CHD) hypertention (H), or cardiac autonomic neuropathy (CAN). Cardiac function was considered to be abnormal if two or more parameters were beyond the mean ± 2 SD found in a group of healthy volunteers matched for age and excluded the complications of CHD, H, CAN by the same criteria. Results; (1) Impaired cardiac function was found in 79% of the patients complicated with CHD and/or H and impaired diastolic function alone was found in 53% of them. Increased interventricular septum thickness was the only finding in changes of cardiac structure. (2) Among the patients without complications of CHD, H, nor retinal and renal microangiopathy, those complicated with CAN had a higher incidence of impaired cardiac function than those without (56% vs 17%). In 61 patients , not complicated with CHD, H, and CAN, 47% showed, impaired cardiac Junction and the incidence was higher in those complicated with retinal and/or renal microangiopathy than in those without (68% vs 17%). Besides, a positive correlation was also found between the severity of cardiac function impairment and microangiopathy. It was concluded that all these fact-ors-CHD, H, CAN, and microangiopathy either alone or in combination contributed to the impairment of cardiac function in diabetic patients.

关 键 词：糖尿病病人 非创伤性 微血管病变 冠心病 高血压 心脏功能 心功能 人心 损害 合并 

分 类 号：R587[医药卫生—内分泌] R544.1[医药卫生—内科学]