肥大乳房和小乳房乳腺组织中雌激素受体的表达  

The expression of the estrogen receptor within the mammary gland of the breast hypertrophy and hypogenesis

作　　者：孙家明[1] 乔群[2] 戚可名[2] 

机构地区：[1]华中科技大学同济医学院附属协和医院整形科,武汉430022 [2]中国协和医科大学协和医院整形科

出　　处：《中华整形外科杂志》2004年第6期415-417,共3页Chinese Journal of Plastic Surgery

摘　　要：目的探讨肥大乳房和小乳房与乳腺组织内雌激素受体含量的关系。方法用葡聚糖包裹活性炭液单点测定法测定肥大乳房和小乳房各13例乳腺组织内雌激素受体的含量。结果肥大乳房组雌激素受体含量为(533±570)fmolmg(注f为万亿分之一),小乳房或乳房萎缩组为(116±086)fmolmg,两组间比较差异有显著性意义(P<005)。结论肥大乳房及巨乳症的发生,可能与雌激素受体含量升高有关;而乳腺组织中雌激素受体含量减少或敏感性较低,可能是乳房发育不全的成因。Objective\ To investigate the expression of the estrogen receptors(ER) in breast hypertrophy and micromastia. Methods\ The quantity of ER within breast tissue in 13 patients with mammary hypertrophy strictly elected was determined using DCC single dot test.The results were compared with that measured in 13 patients with micromastia. Results\ The average of the quantity of the ER was respectively(5 33±5 70) fmol/mg and(1 17±0 86) fmol/mg in mammary hypertrophy ground and in the micromastoa group.There was obvious significant between the two groups in a statistics basis( P <0 05). Conclusions\ The breast hypertrophy is related to the excessive expression of ER within breast tissue,while the micromastia and breast hypotrophy are related to the lower level or the expression inhibition of ER.\;

关 键 词：雌激素受体 肥大 乳腺组织 乳房发育 含量 表达 巨乳症 测定法 显著性 

分 类 号：R655.8[医药卫生—外科学]