沙眼衣原体感染与血清中抗精子抗体相互关系的研究  

Research on the Relationship Between Chlamydia Trachomatis and Antisperm Antibody

作　　者：粟盛梅[1] 刘传爱[1] 赵飞骏[1] 余敏君[1] 占利生[1] 唐双阳[1] 

机构地区：[1]南华大学病原生物学研究所,湖南衡阳421001

出　　处：《南华大学学报（医学版）》2004年第4期440-441,467,共3页Journal of Nanhua University(Medical Edition)

摘　　要：目的 探讨男性不育患者CT感染与血清中AsAb的关系。方法 应用聚合酶链反应(PCR)与ELISA法对177例男性不育患者分别进行CT和AsAb检测。结果 CT阳性者AsAb的阳性率(27.9％)明显高于CT阴性者的AsAb阳性率(8.3％,X2=12.2,P<0.01)。结论 沙眼衣原体感染可增加AsAb的产生,可能与男性不育有关。Objective To investigate the relationship between Chlamydia trachomatis(CT) and Antisperm Antibody(AsAb) in masculine infertile patients. Methods Polymerase chain reaction(PCR) and Enzyme linked immunosorbent assay(ELISA) were separately used to detect the CT and AsAb of 177 masculine infertile patients. Results The positive rate of AsAb in serum of CT infection group and CT uninfection group were 27.9% and 8.3% respectively. There was a significant difference in AsAb presence in serum between the two groups ( P < 0.01) . Conclusion The CT may increase the productivity of AsAb. It may be one of the factors leading to masculine infertility.

关 键 词：沙眼衣原体 抗精子抗体 男性不育 

分 类 号：R374.1[医药卫生—病原生物学]