Syntheses of 1,3,4-Thia(oxa)diazole-substituted Pyrazole Derivatives and Their Fungicidal Activities  

作　　者：WANGWen-yan ZHAOWei-guang LIZheng-ming 

机构地区：[1]StateKeyLaboratoryofElemento-OrganicChemistry,InstituteofElemento-OrganicChemistry,NankaiUniversity,Tianjin300071,P.R.China

出　　处：《Chemical Research in Chinese Universities》2004年第5期543-547,共5页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.2 0 2 0 2 0 0 3) and the state's"86 3"Project(No.2 0 0 1AA2 35 0 11)

摘　　要：A series of 1,3,4-oxadiazole or 1,3,4-thiadiazole-substituted pyrazole derivatives were synthesized from 4-pyrazole formhydrazide; their biological activities were studied. The structures of all the new compounds were confirmed by means of spectroscopic methods and microanalyses. The preliminary bioassay results indicate that some compounds of them have a good fungicidal activity against Phoma asparagi and Physalospora piricola Nose.A series of 1,3,4-oxadiazole or 1,3,4-thiadiazole-substituted pyrazole derivatives were synthesized from 4-pyrazole formhydrazide; their biological activities were studied. The structures of all the new compounds were confirmed by means of spectroscopic methods and microanalyses. The preliminary bioassay results indicate that some compounds of them have a good fungicidal activity against Phoma asparagi and Physalospora piricola Nose.

关 键 词：Pyrazole derivatives Sythesis Fangicidal activity 

分 类 号：O626.21[理学—有机化学] TQ455.47[理学—化学]