Ultrasonic-enhanced Stereoselective Debromination of vic-Dibromides to Alkenes with Metallic Zinc Powder in Aqueous Media  

作　　者：LIPin-hua RAOWan-ping WANGMin WANGLei 

机构地区：[1]DepartmentofChemistry,HuaibeiCoalTeachersCollege,Huaibei235000,P.R.China [2]StateKeyLaboratoryofOrganometallicChemistry,ShanghaiInstituteofOrganicChemistry,ChineseAcademyofSciences,Shanghai200032,P.R.China

出　　处：《Chemical Research in Chinese Universities》2004年第5期598-601,共4页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.2 0 372 0 2 4 ;2 0 172 0 18) ;the Excellent ScientistFoundation of Anhui Province;China(No.2 0 0 10 4 0 ) ;the Natural Science Foundation of the Educational Departm entof AnhuiProvince

摘　　要：Carbon-carbon double bond functional groups are often protected through a popular bromination/debromination method because of their reactivity. An ultrasonic-enhanced stereoselective debromination of vic-dibromides with metallic zinc powder in aqueous media has been developed, which generates E-alkenes with excellent yields. The reactivity of vic-dibromides decreases in the order of 1,2-dibromo-1,2-diphenylethane>1,2-dibromo-1-phenylethane>1,2-dibromo-1,2-dialkylethane.Carbon-carbon double bond functional groups are often protected through a popular bromination/debromination method because of their reactivity. An ultrasonic-enhanced stereoselective debromination of vic-dibromides with metallic zinc powder in aqueous media has been developed, which generates E-alkenes with excellent yields. The reactivity of vic-dibromides decreases in the order of 1,2-dibromo-1,2-diphenylethane>1,2-dibromo-1-phenylethane>1,2-dibromo-1,2-dialkylethane.

关 键 词：Stereoselective debromination vic-Dibromides ALKENES Metallic zinc Ultrasonic irradiation Aqueous medium 

分 类 号：O623.12[理学—有机化学]