Stereoselective Synthesis of (Z)-5-(Trideca-4-enyl)resorcinol and Gibbilimbols A—D  

作　　者：周岭 李洋 曹小平 

机构地区：[1]State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu 730000, China

出　　处：《Chinese Journal of Chemistry》2004年第11期1344-1349,共6页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China (No. QT program 20021001) and the Natural Science Foundation of Gansu Province (No. ZS011-A25-003-Z).

摘　　要：Z)-5-(Trideca-4-enyl)resorcinol (1) and gibbilimbols AD (25) were synthesized in 47%60% yields over 6 steps from commercially available starting materials. The Wittig reaction of various alkyl phosphonium bromides with appropriate aldehydes in the presence of potassium tert-butoxide (t-BuOK) in anhydrous THF solution at room temperature served as the key step, and the result showed that only (Z)-configuration olefins were formed by this procedure. The synthesis of the (Z)-5-(trideca-4-enyl)resorcinol (1) was reported for the first time.Z)-5-(Trideca-4-enyl)resorcinol (1) and gibbilimbols AD (25) were synthesized in 47%60% yields over 6 steps from commercially available starting materials. The Wittig reaction of various alkyl phosphonium bromides with appropriate aldehydes in the presence of potassium tert-butoxide (t-BuOK) in anhydrous THF solution at room temperature served as the key step, and the result showed that only (Z)-configuration olefins were formed by this procedure. The synthesis of the (Z)-5-(trideca-4-enyl)resorcinol (1) was reported for the first time.

关 键 词：(Z)-5-(trideca-4-enyl)resorcinol gibbilimbol SYNTHESIS Wittig reaction 

分 类 号：O621.1[理学—有机化学]