Effect of Long-term Intake of Rare Earth in Drinking Water on Trace Elements in Brains of Mice  

作　　者：刘洁生 申治国 杨维东 车军 谢利民 雷衡毅 

机构地区：[1]DepartmentofBiotechnology,JinanUniversity,Guangzhou510632,China [2]ShenzhenCenterforDiseaseControlandPrevention,Shenzhen518020,China [3]SchoolofEarthandEnvironmentScience,ZhongshanUniversity,Guangzhou510275,China

出　　处：《Journal of Rare Earths》2002年第5期562-564,共3页稀土学报（英文版）

基　　金：ProjectsupportedbytheNaturalScienceFoundationofGuangdongProvince ( 980 3 2 9)andtheMedicalScientificResearchFoundationofGuangdongProvince (A2 0 0 1 6 3 7)

摘　　要：The mice were fed with water dissolved different level Y 3+ (0, 23.25, 2325.00 mg·L -1 ) for seven months, and the levels of trace elements such as Cu, Zn, Mn, Fe, Mg, Ni and Co in brains of F1 generation mice were then determined by POEMS. The results show that, compared with control, significant decreases in levels of Fe and Ni, increase in level of Co are observed, which suggested that Y 3+ may have an effect on the metabolism and distribution of some trace elements in brain, and then lead to changes of physiological function.The mice were fed with water dissolved different level Y 3+ (0, 23.25, 2325.00 mg·L -1 ) for seven months, and the levels of trace elements such as Cu, Zn, Mn, Fe, Mg, Ni and Co in brains of F1 generation mice were then determined by POEMS. The results show that, compared with control, significant decreases in levels of Fe and Ni, increase in level of Co are observed, which suggested that Y 3+ may have an effect on the metabolism and distribution of some trace elements in brain, and then lead to changes of physiological function.

关 键 词：rare earths trace element mouse 

分 类 号：Q42[生物学—神经生物学]