三七止血活血机理的研究Ⅰ．不同剂量三七对小鼠凝血系统的作用  

Hemostasis and Hemoaction of Radix Panax NotoginsengI. Effects of Notoginseng in Different Doses on Mouse's Blood Coagulation System in Vivo

作　　者：杜力军[1,2,3,4] 何卫世 国月英[1,2,3,4] 马茹[1,2,3,4] 

机构地区：[1]中国医学科学院用植物研究所 [2]河南新乡市防疫站 [3]中医研究院西苑医院 [4]新乡市中心医院

出　　处：《中药药理与临床》1995年第3期25-28,共4页Pharmacology and Clinics of Chinese Materia Medica

摘　　要：三七粉口服能够抑制小鼠的凝血，并有一定的量效关系，以２．８ｇ／ｋｇ，５．６ｇ／ｋｇ（相当于成人等效量的４～８倍）时最为明显。这种抗凝血作用主要在内源性凝血系统，并对血小板聚集性有一定的抑制作用（抑制率５８．１％），提示该药所用剂量的大小对于凝血系统有一定的影响。t was showed that the powder of Radix Panax notoginseng (i. g. ) could inhibit the mouse's blood coagulationwith the dose-effect relationship by the experiments of blood coagulation system (BCS). It was the obviously effectsat the dosages of 2.8g/kg and 5.6g/kg (equivalance of 4-8 times adult dose). The action of notoginseng was mainlyon the intrisic coagulation system, also on the platelet aggreegation (inhibiting ratio 58.1%). It is suggested that thedoses of it could affect on BCS.

关 键 词：三七 止血 活血 剂量 小鼠 凝血系统 药理学 

分 类 号：R282.71[医药卫生—中药学]