米非司酮对宫外孕保守治疗的研究与护理  

Conservative treatment and nursing care in ectopic pregnancy with use of Mifepristone

作　　者：叶志杰[1] 王雅静[2] 张全英[1] 李析茜[1] 叶丽娜[1] 

机构地区：[1]吉林大学中日联谊医院,吉林长春130031 [2]吉林大学第二医院,吉林长春130041

出　　处：《吉林医学》2004年第11期6-7,共2页Jilin Medical Journal

摘　　要：目的 :探讨米非司酮对宫外孕保守治疗的有效方案。方法 :对 5 9例生命体征平稳的未破裂型宫外孕患者随机分为 3组 ,每组分别给予口服不同剂量及用法的米非司酮治疗 ,定期复查血HCG及妇科B超 ,进行分析、疗效判定。结果 :①血HCG :B、C两组比较血HCG恢复至正常水平所需时间无明显差异 (P >0 0 5 )。②附件包块 :B组与C组病人治疗前后比较包块的最大径线无差异 (P >0 0 5 ) ,B组与C组病人治疗后包块最大径线无差异 (P >0 0 5 )。③治愈率 :B组较A组亦显著提高 (P <0 0 5 ) ,B、C两组比较 ,治愈率无差异 (P >0 0 5 )。结论 :常规药物流产剂量的米非司酮终止宫外孕妊娠治愈率低 。Objective To assess the impact of mifepristone and nursing care on the conservative treatment of ectopic pregnancy.Method Interventional and random study carried out with 59 patients, the patients were classified into three random groups. Each group had a different dose of mifepristone oral. Each patient vital constants were checked, her blood HCG determined and a gynecologic ultrasound used to determine the value of the annexal mass before rupture.Results A.Groups B and C showed normal levels of blood HCG in similar time intervals (P>0.05).B.The annexal mass diameter in the groups B and C before and after treatment didn't have any significant differences (P>0.05).C.Cure rate:Group B showed higher cure rates than group A (P<0.05), Groups B and C didn't have significant differences in cure rates (P>0.05).Conclusion The contraceptive dose of mifepristone for the treatment of ectopic pregnancy has a low cure rate, but when the dose and duration are increased the cure rate is increases.

关 键 词：米非司酮 宫外孕 血HCG 治愈率 保守治疗 病人 护理 最大 加倍 差异 

分 类 号：R473.71[医药卫生—护理学]