非胰岛素依赖型糖尿病患者头发矿物元素分析  

Hair Mineral Elements Analysis for Non-immune-dependent Diabetes Mellitus

作　　者：黄汉明[1] 梁宝鎏[2] 孙大泽[3] 

机构地区：[1]广西师范大学物理与信息工程学院,桂林541004 [2]香港城市大学物理与材料科学系 [3]天津技术物理研究所,天津300005

出　　处：《微量元素与健康研究》2004年第6期10-12,15,共4页Studies of Trace Elements and Health

基　　金：香港城市大学资助 (No.90 1 0 0 0 7);广西壮族自治区教育厅及科学基金资助 (桂科 0 3 3 90 3 7)

摘　　要：目的 :分析 12 4个案例 (73例糖尿病人和 5 1例对照组健康人 )头发样品中的微量元素铬、锰、铁、铜、锌、硒和宏量元素钙、镁含量水平。方法 :采用催化极谱方法分析。结果 :糖尿病人头发样品中的Cr(0 99± 0 78× 10 -6) ,Mn (1 3± 1 0× 10 -6)和Cu (9 2± 2 7× 10 -6)分别显著低于对照组头发样品中的Cr(1 5 5± 0 97× 10 -6) ,Mn(2 3± 1 6× 10 -6)和Cu(10 4± 2 9× 10 -6) ,显著性水平分别为Cr :P <0 0 0 0 5 ,Mn :P <0 0 0 0 0 4和Cu :P <0 0 3。而糖尿病人头发样品中的Fe (19± 9× 10 -6)则显著高于对照组头发样品中的Fe(16± 8× 10 -6) ,其显著性水平为P <0 0 4。但头发样品中的Zn、Se、Ca和Mg含量水平 ,糖尿病人与健康人之间的差别并不显著。这些结果与其他一些研究者所得的结论是基本一致的。In this investigation, the hair levels of the trace el ements chromium (Cr), manganese (Mn), iron (Fe), copper (Cu), zinc (Zn), seleniu m (Se) and the macro-element calcium (Ca), magnesium (Mg) were determined in 124 subjects (73 diabetics and 51 controls). Samples were analyzed using catalysis polarographic methods. It had been shown that Cr (0.99±0.78×10 -6), Mn ( 1.3±1.0×10 -6) and Cu (9.2±2.7×10 -6) levels in diabetics were sig n ificant lower (P<0.0005, P<0.00004, and P<0.03 for Cr, Mn, and Cu respectively) than that in controls (Cr: 1 .55±0.97×10 -6, Mn: 2.3±1.6×10 -6 and Cu: 10.4±2.9×10 -6 ) while hair Fe significant higher (P<0.04) in diabetics (19 ±9 vs. 16±8×10 -6). However, Zn, Se, Ca and Mg levels in hair showed no significance between diabetics and controls. These results are consistent with r esults obtained by some other researchers.

关 键 词：铬 锰 铜 铁 头发 糖尿病 

分 类 号：R587.1[医药卫生—内分泌]