泡利芬对大鼠脂质过氧化及抗氧化能力的影响  

The Effects of Paolifen on Anti Lipohyperoxygenation in Rat

作　　者：姚林[1] 王广增[1] 赵伯阳[1] 耿辉[1] 

机构地区：[1]华北煤炭医学院医学系

出　　处：《中国实验动物学杂志》1998年第3期142-145,共4页Chinese Journal of Laboratory Animal Science

摘　　要：研究泡利芬对大鼠的血清及肝脏超氧化物歧化酶（简称ＳＯＤ及脂质过氧化物简称ＬＰＯ）影响及作用机制。本研究采用微量快速法测定ＳＯＤ活性，用硫代硫酸钠荧光法测定ＬＰＯ的最终产物丙二醛含量。泡利芬实验组动物血清及肝脏ＳＯＤ活性均比对照组高，且有显著意义，而ＬＰＯ含量较对照组下降也有显著性意义。泡利芬具有良好的抗氧化、清除自由基和抗衰老作用，对机体的延年益寿和抗老保健具有特别重要意义。The study was carried out to assess the effects of Paolifen on the activities of Super oxide Dismutase (SOD) and the contents of Lipid Peroxidize (LPO) of rat,The activities of SOD was determined with fast method.And malondialdehyde (MDA) was determined by TBA fluorescence,The SOD activities of rat liver and serum was a significant increase in the experimental groups of Paolifen (P<0.05).The contents of LPO in three groups taking Paolifen were much lower than that of the control group.It is suggested that Paolifen have an action of anti oxidate,scavenging the free radicals.

关 键 词：LPO 对照组 大鼠 血清 肝脏 脂质过氧化 抗老 丙二醛含量 SOD活性 快速法 

分 类 号：Q554[生物学—生物化学] R285.5[医药卫生—中药学]