2型糖尿病心肌缺血的相关因素分析  

Multiple factors related analysis of myocardial ischemic in patients with mellitus diabetes.

作　　者：游志清[1] 张琴[2] 辛火[1] 金小岚[1] 郭蔚[1] 程莹[1] 

机构地区：[1]成都军区总医院,四川成都610083 [2]成都市第四人民医院,四川成都610036

出　　处：《四川医学》2004年第12期1298-1300,共3页Sichuan Medical Journal

摘　　要：目的　探讨糖尿病心肌缺血的相关因素。方法　按 12导联心电图 ,将 93例糖尿病患者分为无心肌缺血组 (A组 )和心肌缺血组 (B组 )。两组病人均完成血压、心脏自主神经功能、尿白蛋白排泄率 (UAE)、红细胞山梨醇(RBCS)、糖化血红蛋白 (HbAlc)、血总胆固醇 (TC)、甘油三酯 (TG)、高密度脂蛋白 (HDL)及其亚类 (HDL3 c及HDL2 c)、低密度脂蛋白 (LDL)、血浆镁 (Mg) ,血浆纤维蛋白原 (Fg)测定。结果　与A组比较 ,B组的病程显著较长 ,收缩压和舒张压 ,UAE ,HbAlc ,RBCS ,TG ,TC ,LDL和Fg显著升高 ,而心脏自主神经功能、HDL和Mg显著降低 (P <0 0 5或 0 0 1)。两组间性别构成、体重指数、年龄、HDL2 c和HDL3 c无显著差别。Logistic逐步回归分析示与心肌缺血密切相关的主要因素依次为UAE、心脏自主神经病变 (CAND)、TG、dBp和HDL。结论　UAE、dBp和TG升高 ,HDL降低 ,以及CAND是糖尿病人心肌缺血的主要相关因素。防治糖尿病心肌缺血除了控制血糖外 ,还应控制尿白蛋白排泄率和血压 ,调节血脂 。Objective To explore the related factors of myocardial ischemic.Methods According to 12-conductor ECG,93 cases patients with type 2 diabetes mellitus were divided into two groups:group A,none myocardial ischemic,61(20/42)cases;group B,myocardial ischemic,31(9/22)cases.All patients had been finished,duration,systolic BP(SBP),diastolic BP(DBP),BMI,cardiac sympathetic activities(SA),cardiac parasympathetic activities(PA),urinary albumin excretion(UAE),HbAlc,red cell sorbitol (RBCS),total cholesterol(TC),triglycerol(TG),low density lipoprotein cholesterol (LDL-c),high density lipoprotein cholesterol(HDL-C)and its composition HDL2-c and HDL3-c,plasma fibrinogen(Fg)and magnesium(Mg).Results Showed that the values of duration,SBP and DBP,UAE,RBCS,TG,TC,HbAlc,LDL and Fg were significant higher,but the values of SA,PA,HDL-c and Mg were significant lower in the group B,when contrasted with group A,Between two groups there were no significant variety in ages BMI,sex composition,HDL2-c and HDL3-c Logistic regression suggested that factors related mainly with myocardial ischemic were UAE,cardiac autonomic neuropathy,TG,DBP and HDL.Conclusion These results suggested that the main dangerous factors of myocardial ischemic were increase in UAE,DBP and TG,decrease in HDL,and cardiac autonomic neuropathy.

关 键 词：糖尿病 2型 心肌缺血 

分 类 号：R587.2[医药卫生—内分泌]