两种治疗方法对老年恶性胸腔积液疗效的对比研究  

Comparison of two methods to treat malignant pleural effusion in senile patients

作　　者：何华[1] 刘齐宁[1] 王惠芳[1] 候敏全[1] 

机构地区：[1]西安交通大学第一医院老年内科,陕西西安710061

出　　处：《中国现代医学杂志》2004年第23期89-91,共3页China Journal of Modern Medicine

摘　　要：目的探讨胸腔内置入单腔中心静脉导管治疗老年恶性胸腔积液的效果。方法60例中等量以上恶性胸腔积液老年患者,随机分为两组,C组(n=30)采用中心静脉导管置管定时引流胸腔积液并注入化疗药物;D组(n=30)采用穿刺针抽完胸腔积液后注入化疗药物。根据WHO对癌性渗液的疗效评定标准判定疗效。结果两组患者注药次数无显著性差异(P>0.05),总有效率C组(CR+PR)为83.3%(25/30),D组为(CR+PR)56.7%(17/30),两组疗效有显著性差异(P<0.05),不良反应C组明显低于D组(P<0.05)。结论采用胸腔内置管治疗老年恶性胸腔积液,具有操作简便、病人痛苦小,化疗效果好,不良反应少,是治疗老年恶性胸腔积液的有效方法之一。Objective: To explore the effect of putting central venous catheter into pleural cavity in the senile patients with malignant pleural effusion. Methods: 60 senile patients with malignant pleural effusion were randomly divided into two groups. After malignant pleural effusion were drained by the pleural catheter, the drugs were infused into pleural cavity in the group C (n =30). After the malignant pleural effusion were drawn by puncture needle, the drugs were infused into pleural cavity in the group D (n =30). The effect was evaluated according to the standard of malignant pleural effusion of WHO. Results: There was no significant difference in the times of injecting drug in the two groups (P >0.05). Total efficiency in the group catheter were 83.3%, while in the group drawn effusion were 56.7%, Which had significant difference (P <0.05). The adverse responses in group C were significantly lower than those in group D (P <0.05). Conclusion: Treating the senile patients with malignant pleural effusion by implanting pleural catheter is one of the effective method, which has the characters of simple manipulation, painlessness, good chemical therapy effect and few adverse response.

关 键 词：导管 恶性胸腔积液 引流 老年 

分 类 号：R561[医药卫生—呼吸系统]