氨基磺酸催化合成氯乙酸正丁酯  

Synthesis of n-Butyl Chloroacetate Catalyzed by Amino Sulfonic Acid

作　　者：李旺英[1] 俞善信[2] 文瑞明[1] 

机构地区：[1]湖南城市学院化学与环境工程系,湖南益阳413049 [2]湖南师范大学化学化工学院,湖南长沙410081

出　　处：《广州化学》2004年第4期1-4,共4页Guangzhou Chemistry

基　　金：湖南省科技计划资助项目(03JZY3034)

摘　　要：氨基磺酸能够代替硫酸作为酯化催化剂。研究了以氨基磺酸为催化剂,氯乙酸与正丁醇合成氯乙酸正丁酯。研究了反应的影响因素和催化剂的重复使用性能。当氯乙酸、正丁醇和氨基磺酸的摩尔比为0.05:0.15:0.00773,回流分水90min时,酯收率达82.4%。并以氨基磺酸为催化剂合成了氯乙酸异丁酯、氯乙酸仲丁酯、氯乙酸正戊酯、氯乙酸异戊酯和氯乙酸2-戊酯。Amino sulfonic acid can be used as catalyst for esterification instead of sulphuric acid. The n-butyl chloroacetate was synthesized by chloroacetic acid and n-butanol, in which amino sulfonic acid was used as catalyst. The influent factors of reaction and the reuseability of the catalyst were investigated. The yield of the ester could reach 82.4% when the mole ratio of chloroacetic acid, n-butanol and amino sulfonic acid were 0.05:0.15:0.0073, with refluxing and water segregating for 90min. The iso-butyl chloroacetate, sec-butyl chloroacetate, n-amyl chloroacetate, iso-amyl chloroacetate and 2-amyl chloroacetat were also synthesized with the same catalyst.

关 键 词：氯乙酸正丁酯 合成 氨基磺酸 催化 

分 类 号：O643.38[理学—物理化学]