天麻钩藤饮对肝阳上亢型高血压病患者血压及血清SOD的影响  

The Effects of Gastrodia and Uncaria Beverage on Blood Pressure and Serum SOD Activity of Patients with Hypertension in the Pattern of Ascendant Liver Yang

作　　者：刘卫平[1] 蔡昌龙[1] 李明月[2] 谭海彦[1] 张臣[1] 

机构地区：[1]中南大学湘雅医院中西医结合研究所,湖南长沙410008 [2]湖南省邵阳市第一人民医院,湖南邵阳422001

出　　处：《湖南中医学院学报》2004年第6期44-45,56,共3页Journal of Hunan College of Traditional Chinese Medicine

基　　金：湖南省科技厅科技计划项目 ( 0 3ssy40 0 8)

摘　　要：目的探讨天麻钩藤饮对高血压病 (肝阳上亢型 )患者疗效和血清超氧化物歧化酶 (SOD)活性的影响 ,为临床高血压病患者的治疗提供有力的理论依据。方法将 60例患者随机分为天麻钩藤组 (治疗组 ,3 0例 )和对照组 ( 3 0例 ) ,4周后 ,观察两组治疗前后血压的改变及血清SOD的改变 ,并与 1 0例正常人血清SOD作比较。结果两组患者治疗后血压均明显降低 ,两组比较无显著性差异 (P >0 .0 5 ) ,天麻钩藤 (治疗 )组和对照组的SOD活性在治疗前分别为 ( 85 .6± 1 1 .2 )U mL和 ( 86.3± 1 2 .5 )U mL ,在治疗后分别为 ( 1 0 5 .1±1 2 .8)U mL和 ( 95 .1± 1 3 .2 )U mL ,治疗后两组比较有明显差异 (P <0 .0 1 )。结论天麻钩藤饮能显著降低高血压病患者血压 ,并能通过提高SOD活性保护机体 。Objective To investigate the effects of Gastrodia and Uncaria Beverage (GUB) on blood pressure and serum SOD Activity of patients with hypertension in the pattern of ascendant Liver Yang.Methods Sixty cases with hypertension were randomly divided into two groups,with 30 cases in each group.Group 1 was treated with GUB (TG) and group 2 was given the routine therapy as control (CG).The treatment was lasted for 4 weeks.Observed were the changes in blood pressure and the activity of SODin serum,determined before and after the therapy respectively.Results Blood pressure was significantly declined following the treatment in all the cases of both groups,with no significant difference between them.However,the activity of SOD was significantly higher in the cases of TG than that in CG (P<0.01) after treatment, being (105±12.8)U/mL and (95.1±13.2)U/mL respectively,while there was no obvious difference present between the 2 groups before treatment (being 85.6±11.3 U/mL and 86.3±12.5 U/mL respectively).Conclusions GUB can significantly decline blood pressure for cases with hypertension and enhance the activity of SOD to improve the antioxidation ability of the body.

关 键 词：患者 高血压病 天麻钩藤饮 治疗后 血清SOD 肝阳上亢型 对照组 SOD活性 显著性差异 机体 

分 类 号：R544.1[医药卫生—心血管疾病] R277[医药卫生—内科学]