心宁胶囊中人参皂苷Rg_1的HPLC测定  

Determination the Content of Ginsenosides Rg, in Xinning Capules by HPLC

作　　者：王隶书[1] 程东岩[1] 李阳[2] 

机构地区：[1]吉林省中医中药研究院,长春130021 [2]吉林工大医院

出　　处：《中国药师》2005年第1期23-25,共3页China Pharmacist

摘　　要：目的:建立心宁胶囊中人参皂苷Rg1的含量测定方法。方法:HPLC法,流动相:乙腈-0.4％磷酸水溶液(20.5:79.5)为流动相;检测波长为203nm;柱温40℃。结果:人参皂苷Rg1线性范围为0.392μg-4.704μg,平均回收率99.8％,RSD为2.23％。结论:方法可靠,简单可行,为控制心宁胶囊的内在质量提供了科学依据。Objective: To establish a method for determining Ginsenosides Rg1 in Xinning capules. Method: HPLC was used with mobile phase: acetonitrile -0. 4% phosphoric acid solution(20. 5: 79. 5) ,the detecting wavelength was at 203 nm. Result: The standard curve was linear within a range of 0. 392-4. 704 μg. The average recovery and RSD were 99. 8% and 2. 23% , respectively. Conclusion : This method is accurate and reliable, and can provide a scientic foundation for controlling the quality of Xinning capules.

关 键 词：心宁胶囊 人参皂苷RG1 高效液相色谱法 

分 类 号：R927.2[医药卫生—药学]