紫外分光光度法测定盐酸川芎嗪氯化钠注射液中盐酸川芎嗪含量  

Determination the Content of Ligustrazine Hydrochloride in Ligustrazine Hydrochloride and Sodium Chloride Injection by Ultraviolet Spectrophotometry

作　　者：胡珊[1] 程义琳[1] 何秀国[1] 余忠[1] 

机构地区：[1]随州市中心医院药剂科,湖北随州441300

出　　处：《中国药师》2005年第1期25-26,共2页China Pharmacist

摘　　要：目的:建立盐酸川芎嗪氯化钠注射液中盐酸川芎嗪的含量检测方法。方法:采用紫外分光光度法,检测波长为295nm。结果:盐酸川芎嗪在3.0-15.0μg·ml-1范围内呈良好线性关系(r=1.0000,n=5),回收率为100.3％,RSD为0.65％(n=5)。结论:本法操作简便、快捷,结果准确,尤适用于药厂、医院对该制剂半成品的质量控制和快速分析。Objective: To establish a method for determining the content of ligustrazine hydrochloride in ligustrazine hydrochloride and sodium chloride injection. Method: The ultraviolet spectrophotometry was used. The detecting wavelength was at 295 nm. Result: The linear range of ligustrazine hydrochloride was 3.0-15.0 μg·ml-1 (r = 1.000 0,n =5). The average recovery was 100.3% ,RSD = 0.65%. Conclusion: This method is simple, rapid, and accurate, and suitable for the the content determination of this injection.

关 键 词：川芎嗪氯化钠 盐酸 川芎嗪 盐酸 紫外分光光度法 

分 类 号：R927.2[医药卫生—药学]