急性心肌梗塞病人白细胞变形能力的测定及其临床意义  

LEUKOCYTE DEFORMABILITY IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AND ITS CLINICAL SIGNIFICANCE

作　　者：刘成玉[1] 陈作元[1] 王雷[2] 谭润鸾[1] 张华[2] 

机构地区：[1]青岛医学院诊断学教研室 [2]青岛市市立医院

出　　处：《青岛医学院学报》1993年第4期299-302,共4页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：检测46例急性心肌梗塞(AMI)病人,白细胞变形能力(LD)的变化。结果显示,AMI病人LD较对照组明显降低(P<0.001);有室性心律失常者LD较无室性心律失常者明显降低(P<0.001)。LD随着血浆纤维蛋白原(Fg)、总胆固醇(TC)、甘油三酯(TG)、脂质过氧化物代谢产物丙二醛(MDA)水平的增高和血浆镁(Mg^(2+))浓度的降低而降低。结果提示,在预防和治疗AMI过程中,提高LD,对改善微循环、增加缺血心肌的血流、缩小梗塞面积和改善预后都具有重要的临床意义。Leukocyte deformabiliyt (LD) was measured in patients with myocardial infarction (AMI). The results showed that LD in the patients was significantly lower than that in normal controls (P<0.001) and that LD in patients with ventricular arrhythmia was significantly lower than that in patients without the trouble (P<0.001). LD in the pa- tients would further reduce with the rise of the levels of total cholesterol (TC), triglyc- eride (TG), malondialdehyde (MDA) on fibrinogen (Fg) and the reduction of plasma magnesium (Mg^(2+)) concentration. The results indicate that enhancing the LD in the pro- cess of prevention and treatment of AMI may be helpful in improving the microcircu- lation, increasing the blood flow in capillaries in ischemic myocardium, reducing the area of infarction and improving the prognosis of the disease.

关 键 词：心肌梗塞 白细胞变形能力 测定 临床 

分 类 号：R542.220.4[医药卫生—心血管疾病]