荷移光度法测定药片中的安乃近含量  

DETERMINATION OF METAMIZOLE SODIUM BY CHARGE TRANSFER SPECTRAL METHOD

作　　者：刘雪静[1] 黄薇[1] 

机构地区：[1]山东枣庄学院化学系,山东枣庄277100

出　　处：《内蒙古师范大学学报（自然科学汉文版）》2004年第4期414-415,423,共3页Journal of Inner Mongolia Normal University(Natural Science Edition)

基　　金：山东省教育厅科技计划项目(J02H57)

摘　　要：用荷移光度法研究了氯冉酸与安乃近的荷移反应,确定了反应条件.氯冉酸与安乃近在乙醇介质中形成络合物,最大吸收波长为530nm,表观摩尔吸光系数为9.07×102L·mol-1·cm-1.安乃近浓度在0.02～0.20g·L-1时,符合比尔定律.该方法操作简单,重现性好,回收率和灵敏度高,相对标准偏差为1.3%,结果令人满意.Based on the study of the reaction between chloranilic acid and Metamizole Sodium,a new method for determining Metamizole Sodium under optimized conditions is proposed in this paper.Through the proposed method,the following results are obtained.In the presence of ethanol,the apparent molar absorptivity of the CT complexes at 530 nm is 9.07×10~2 L·mol^(-1)cm^(-1).Beer's law is obeyed in the range of 0.02～0.20 g·L^(-1) Metamizole Sodium.The relative standard deviation is 1.3%(n=6).The proposed method is proved to be a simple,sensitive and reproducible method for the determination of the Metamizole Sodium in ethanol with satisfactory results.

关 键 词：安乃近 药片 含量 比尔定律 最大吸收波长 乙醇 荷移反应 光度法 氯冉酸 相对标准偏差 

分 类 号：O657[理学—分析化学]