海岛地区脂肪肝患者的血清流行病学研究  

A Seroepidemiology Study on Insular Fatty Liver Sufferer

作　　者：龚戬芳[1] 江飞君[1] 王晓莺[1] 郑舟军[1] 

机构地区：[1]浙江海洋学院医学院,浙江舟山316004

出　　处：《浙江海洋学院学报（自然科学版）》2004年第3期237-239,265,共4页Journal of Zhejiang Ocean University(Natural Science Edition)

摘　　要：为了探讨海岛地区脂肪肝患者多项生化指标的变化趋势,应用血清流行病学调查方法,对脂肪肝患者进行实验室多项血清学指标检测,并与非脂肪肝患者比较,结果用SPSS.10软件包进行处理分析,结果表明:(1)脂肪肝的检出率为30.14%;各年龄组间的检出率无明显差异(P>0.05)。(2)脂肪肝的检出率随着体重指数的增高而增加;肥胖组与非肥胖组脂肪肝的检出率有明显差异(P<0.05)。(3)除白蛋白(ALB)、球蛋白(GLB)及其比值(A/G)外,脂肪肝患者的其他项目均明显高于非脂肪肝患者(P<0.01);谷丙转氨酶(ALT)升高的相对量较谷草转氨酶(AST)高。(4)脂肪肝患者的血细胞数量在一年前后有所改变,其中,红细胞(RBC)、白细胞(WBC)略有下降,血小板(PC)明显增加(P<0.01)。海岛地区脂肪肝的发生出现明显低龄化;肥胖是脂肪肝发生的重要危险因素;脂肪肝对患者的肝功能和造血功能造成一定的影响。In order to explore the changes of the indexes of serology on fatty liver sufferer,by applying seroepidemiology to collect the data about the indexes of serology on fatty liver and non-fatty liver sufferers and using the software of SPSS.10 to analyse the outcome,results show that:(1)The mass incidence of fatty liver was 30.14 %,and there weren′t difference among different age(P>0.05).(2) The detectable rate of fatty liver increased with the body mass index(BMI).A remarkable difference could exist between the two groups of fatness and nonfatness(P<0.05). (3)The indexes of serology of persons with fatty liver were higher than those of persons with nonfatty liver except ALB,GLB and A/G,and the relatively quantity of ALT is much than that of AST.(4)The quantity of blood cells on fatty liver sufferers has changed in a year,and RBC,WBC were lower,however PC has been higher(P<0.01),and that the sufferers of fatty liver take obviously place in lower age.The fatness is very important risk-factor of fatty liver,and the impacts of fatty liver on liver and blood exist to some extent.

关 键 词：脂肪肝患者 检出率 海岛地区 血清流行病学 肥胖 血清学指标 ALB 发生 数量 球蛋白 

分 类 号：P641[天文地球—地质矿产勘探] R575.5[天文地球—地质学]