Cleavage of DNA by a New Mixed-ligand Cu(Ⅱ) Complex  

作　　者：QingHuaZHOU PinYANG 

机构地区：[1]InstituteofMolecularScience,ChemicalBiologyandMolecularEngineeringLaboratoryofEducationMinistry,ShanxiUniversity,Taiyuan030006

出　　处：《Chinese Chemical Letters》2005年第1期81-84,共4页中国化学快报（英文版）

基　　金：support of the National Natural Science Foundation of China(No:20171031);the Shanxi Provincial Natural Science Foundauon for Youth(No:20011007)

摘　　要：Cleavage of DNA pUC19 by [Cu(saldien)(NH3)]Cl2 (here, saldien=bis(salicylicdene)- diethylenetriamine) was investigated at different pHs, times, concentrations, and 37℃. It was found that the copper(Ⅱ) complex could cleave DNA without added coreactants.Cleavage of DNA pUC19 by [Cu(saldien)(NH3)]Cl2 (here, saldien=bis(salicylicdene)- diethylenetriamine) was investigated at different pHs, times, concentrations, and 37℃. It was found that the copper(Ⅱ) complex could cleave DNA without added coreactants.

关 键 词：Copper(Ⅱ) complex cleavage of DNA saldien. 

分 类 号：Q523[生物学—生物化学]