心力衰竭病人血甲状腺激素、促甲状腺素的测定及其意义  

Change and meaning of FT_3, FT_4, FSH in patients with congestive heart failure

作　　者：邢俊杰[1] 邵冰[1] 张湘兰[1] 袁凤贤[2] 邹德玲[2] 

机构地区：[1]沈阳医学院附属第二医院心内科,辽宁沈阳市110002 [2]中国医科大学附属第二医院心内科,辽宁沈阳市110016

出　　处：《心血管康复医学杂志》2004年第6期530-532,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:探讨充血性心力衰竭(CHF)病人血清游离甲状腺激素(FT3、FT4)、促甲状腺激素(TSH)浓度的变化及其意义。方法:用放免法测定77例CHF病人及30例正常人血清FT3、FT4、TSH的浓度,并对11例Ⅲ或Ⅳ级CHF病人治疗前、后及各种原发病致CHF时的FT3、FT4、TSH浓度进行比较。结果:CHF组FT3降低(P<0.01),FT4及TSH正常。严重CHF可伴有FT4降低(P<0.01)。心衰越重,FT3降低越明显(P<0.05)。结论:FT3、FT4可作为CHF病情程度判断的一个指标。Objective: To explore the change and meaning of the serum free thyroid hormone [free triiodothyronine (FT3), free tetraiodothyronine (FT4), thyroid stimulating hormone (TSH)] in patients with congestive heart failure (CHF). Methods: The serum concentration of thyroid hormone before and after treatment was measured and compared by radioimmunossay in patients with CHF (n=77) and in healthy control subjects (n = 30). Results: The serum concentration of FT3 was lower in patients with CHF than those of normal control (P<0. 01). The serum concentration of FT4 decreased (P<0. 01) in severe CHF patients, the severer the CHF was, the lower the concentration of FT3 (P<0. 05). When cardiac functional improvement the FT3 concentration increased (P<0. 05). Conclusion: The finding suggests that the serum concentration of FT3, FT4 may be an index in evaluating the state of illness in patients with CHF.

关 键 词：CHF FT3 FT4 病人 TSH 促甲状腺素 人血清 游离甲状腺激素 心力衰竭 治疗前 

分 类 号：R541[医药卫生—心血管疾病] R446[医药卫生—内科学]