转化生长因子β_1与缺血缺氧性脑损伤  

Transforming growth factor-beta 1 and hypoxic-ischemic brain damage

作　　者：李小权[1] 孙晓勉[1] 杨周岐[1] 

机构地区：[1]西安交通大学第一医院儿科,陕西西安710061

出　　处：《国外医学（妇幼保健分册）》2004年第6期326-328,共3页Foreign Medical Sciences (Section of Maternal and Child Health)

摘　　要：转化生长因子β1是一种具有多功能的细胞因子,在正常脑细胞中表达极少,在脑细胞发生缺血缺氧损伤后表达明显增多。转化生长因子β1可以通过多种途径促进缺血缺氧性脑损伤所引起的神经细胞的康复。该文对这方面的研究进展作以综述。Transforming growth factor beta 1(TGF β 1)has diverse and multiple functions. The expression of TGF β 1 is few in normal brain tissues. In recent years, studies have demonstrated that TGF β 1 level enhances in hypoxic ischemic brain damage(HIBD), TGF β 1 can accelerate renovation of the nerve cells injured by hypoxia and ischemia through many approaches. In this article, we reviewed the beneficial effects of TGF β 1 on HIBD.

关 键 词：转化生长因子 缺血缺氧性脑损伤 

分 类 号：R722[医药卫生—儿科] R743.31[医药卫生—临床医学]