一种1,10菲啰啉-5,6-二酮及其单肟的高效合成方法  

An Efficient Synthesis Method for 1,10-Phenanthroline-5,6-dione and Its Mono oxime

作　　者：张智斌[1] 闫文鹏[1] 樊美公[1] 

机构地区：[1]中国科学院理化技术研究所,北京100101

出　　处：《应用化学》2005年第1期103-104,共2页Chinese Journal of Applied Chemistry

基　　金：国家高技术研究发展计划("八六三"计划) (2002AA305301);国家自然科学基金(20302008)资助项目

摘　　要：phenanthroline(1) was oxidized by a mixture of concentrated sulfuric acid and concentrated nitric acid in the presence of sodium bromide to yield 1,10 phenanthroline 5,6 dione(2) in 90%. Compound 2 gave a mono oxime(3) hydrochloric salt in nearly quantitive amount by reacting with equal molar hydroxylamine hydrochloride. The structures of the compounds were characterized by IR and 1 H NMR spectroscopy. The method is more simple and efficient.phenanthroline(1) was oxidized by a mixture of concentrated sulfuric acid and concentrated nitric acid in the presence of sodium bromide to yield 1,10 phenanthroline 5,6 dione(2) in 90%. Compound 2 gave a mono oxime(3) hydrochloric salt in nearly quantitive amount by reacting with equal molar hydroxylamine hydrochloride. The structures of the compounds were characterized by IR and 1 H NMR spectroscopy. The method is more simple and efficient.

关 键 词：菲啰啉二酮 菲啰啉二酮单肟 合成 

分 类 号：O626.3[理学—有机化学]