HA型血液灌流器对毒鼠强吸附性的研究  

作　　者：CHENZhi WANGHanbin YANGHongjun QIUZewu ZHANGLinzhi SUNChengwen 

机构地区：[1]TheAffiliatedHospitalofAcademyofMilitaryMedicalSciences,Beijing100039,China [2]InstituteofRadiationMedicine,theAcademyofMilitaryMedicalScience,Beijing100850,China

出　　处：《世界急危重病医学杂志》2005年第1期509-509,共1页internationl journal of emergency and critical care medicine

摘　　要：Objective To evaluate the extraction efficiency of HA sterile Haemoperfusion Cartridge for treatment of tetramine intoxication and investigate the relationship between the plasma concentration of TETS at the beginning of HP and adsorbed TETS amounts by resin cartridges. Patients and Methods Twelve patients of tetramine poisoning were treated with HA sterile Haemoperfusion Cartridge (ploy meric adsorbents). TETS in blood samples at the time of hospitalization, before and after HP, and in cartridges were quantitatively analysed with gas chromatography spectrometry. Extraction method in Haemoperfusion Cartridge was established. Results (1)The reduction of plasma concentration of TETS was associated with interval and times of haemoperfusion. (2)Ethyl actate percolation could extract 99% tetramine in cartridges. (3)With two sizes (330 ml or 230 ml) of HA sterile Haemoperfusion Cartridges could remove (2.03+0.999) mg and (1.508+_0.620) mg tetramine in blood respectively, but showed no statistical difference (19>0.05) .(4)Lineal correlation analysis indicated that the adsorbed TETS amount in Cartridge was positive correlated with the plasma concentration of TETS before HP. Conclusions (1)Haemoperfusion can remove tetramine in human body effectively . (2)Ethyl actate percolation is a effective,easy and safe method for extracting tetramine on resin adsorbents. (3)The adsorbed TETS amount in cartridge is linearly related to the plasma concentration of TETS. HP with small size cartridge (HA-230 ml) more times could possibly improve curative effect and save medical expenses.

关 键 词：HA 血液灌流 HP 毒鼠强 研究 吸附性 

分 类 号：R595[医药卫生—内科学] R575[医药卫生—临床医学]