糖尿病与肥胖、血脂、血压的关系  

Effects of obesity on dyslipidemia and hypertension in type 2 diabetes

作　　者：密红翠[1] 丁建生[2] 吴纬[3] 赵春林[1] 张小丰[1] 成仲[1] 

机构地区：[1]解放军第一医院,甘肃兰州730030 [2]兰州医学院,甘肃兰州730000 [3]兰州医学院第一附属医院,甘肃兰州730000

出　　处：《解放军保健医学杂志》2004年第4期211-213,共3页Journal Of Health Care And Medicine in Chinese Pla

摘　　要：目的 探讨2型糖尿病(DM)的体重和血脂、血压的关系。方法 DM患者66例,糖耐量减低(IGT)59例,糖耐 量正常者70例共三组。各组按BMI≥25及≤24.9分为肥胖(H组)及非肥胖(L组)两组。测定每例的腰围(W)、腰臀比 (WHR)、血脂(TG,TC,HDL-C,LDL-C)和血压(SBP和DBP)。统计用方差分析和多重比较法。结果 ①WHR糖尿病肥胖 组明显大于对照肥胖组,P<0.05。②TG肥胖组高于非肥胖组,DM非肥胖组明显高于IGT非肥胖组和对照非肥胖组,P <0.05。③血压在DM和IGT肥胖组明显高于非肥胖组,P<0.05。DM的血压明显高于IGT组,P<0.05。结论 肥胖 患者血脂紊乱和血压增高的患病率增高,尤其是腹型肥胖者明显。WHR增大和TG、血压增高是2型糖尿病的危险因素。Objective To investigate the effects of body mass index (BMI) and waist-hip ratio (WHR) on dyslipidemia and hypertension in type 2 diabetes . Methods 66 diabetics (group A),59 IGT (group B)and 70 normal glucose tolerance (group C), indentified by OGTT, were subdivided into overweight (BMI≥25, H) and non-overweight (BMI≤24. 9, L) groups respectively. WHR,systolic and diastolic blood pressure (SBP and DBP) and postprandial serum lipid(triglyceride TG, total cholesterol TC, HDL-C and LDL-C) were measured for all subjects . Variance analysis and least significant difference LSD were performed to evaluate the relationships of serum lipids, blood pressure with BMI and WHR. Results ① WHR of the 3H groups (AH, BH, CH) were significantly greater than the non-overweight groups (AL, BL, CD , the WHR of AH group was significantly greater than CH group, and AL group greater than CL group, P < 0. 05 .② TG of the 3H groups were higher than BL and CL groups,and TG of AL group was comparable to AH group,higher than BL and CL groups , P< 0. 05 .③ Both SBP and DBP of AH and BH groups were significantly higher than that of AL and BL groups , P < 0. 05 . The blood pressure of DM (both overweight and non-overweight) was significantly higher than that of IGT, P < 0. 05 . Conclusions Dyslipidemia and high blood pressure are closely correlated with obesity, especially central obesity. WHR, TG and elevated blood pressure were risk factors in type 2 diabetes.

关 键 词：糖尿病 高血压 血脂紊乱 

分 类 号：R587.1[医药卫生—内分泌]