新型C10高碳糖的NMR和ESI-MS/MS研究  

SYNTHESIS OF A NEW C10 HIGHER CARBON SUGAR AND ITS STRUCTURE ELUCIDATION BY NMR AND ESI-MS/MS

作　　者：邹大鹏[1] 康建勋[1] 刘宏民[1] 许卫超[1] 张慧君[1] 张碧[1] 

机构地区：[1]郑州大学化学系,河南郑州450052

出　　处：《波谱学杂志》2004年第4期397-403,共7页Chinese Journal of Magnetic Resonance

基　　金：国家自然科学基金资助项目 ( 2 0 2 72 0 5 4)

摘　　要：利用 1 ,2 异丙基 5位苯甲酰基α D 呋喃型木糖合成了具有潜在抗菌活性的C1 0高碳糖 ,检测了该化合物的1 H、1 3CNMR和ESI MS/MS图谱 ,确证了该化合物的结构 ,通过DEPT和1 H 1 HCOSY ,HMQC ,HMBC等 2DNMR技术对其1 H和1 3CNMR数据进行了全归属和较详细的解析并探讨了其ESIPDC is commonly used to oxidate the hydroxy residue in carbohydrates to produce the corresponding ketone. Treatment of 1, 2-isopropylidene-5-O-benzoyl-α-D-xylofuranose with PDC in CH_2Cl_2 usually yields ketone. It was found in this study, however, a new type higher carbon sugar was obtained when the solvent in the above reaction was changed. The structure of the new higher carbon sugar was elucidated by NMR and ESI-MS/MS. The complete assignment of ~1H and ^(13)C NMR chemical shifts of this compound was obtained using 2D NMR techniques, including ~1H-~1H COSY, HMQC and HMBC.

关 键 词：ESI-MS NMR技术 HMBC 酰基 化合物 ^13C 呋喃 抗菌活性 质谱 图谱 

分 类 号：O626[理学—有机化学] R284.1[理学—化学]