脉冲振荡法在慢性阻塞性肺疾病中的应用和临床意义  

Application and clinical value of impulse oscillometry in chronic obstructive pulmonary disease

作　　者：邓静[1] 陈余清[1] 卢杨[2] 王爱华[2] 

机构地区：[1]蚌埠医学院附属医院呼吸科,安徽蚌埠233004 [2]蚌埠医学院附属医院肺功能室,安徽蚌埠233004

出　　处：《蚌埠医学院学报》2005年第1期24-26,共3页Journal of Bengbu Medical College

摘　　要：目的 :探讨脉冲振荡法 (IOS)在慢性阻塞性肺疾病 (COPD)中的特征性改变及临床应用价值。方法 :用IOS测定 5 0名健康人、110例COPD患者的呼吸阻抗及参数结构图 ,与传统肺量计法肺功能检测中FEV1/FVC %、FEV1/Pred %等指标比较。结果 :与健康组相比 ,COPD组周边气道阻力和共振频率明显增加 ,周边电抗下降明显 ,中心气道阻力部分增加 ,IOS输出图形有特征性改变。结论 :IOS检测可较好的反映出气道阻力尤其是小气道阻力变化和肺顺应性的变化 ,对COPD有较大的临床诊断价值。Objective:To explore the clinical value and specific changes of impulse oscillometry(IOS) in chronic obstructive pulmonary disease(COPD).Methods:The IOS indices of 50 normal cases and 110 cases of COPD were measured and compared with the traditional lung function indices including FEV 1/FVC%,and FEV 1/Pred%.Results:Compared with normal cases,the peripheral resistance and resonant frequency(Fres) of the 110 patients with COPD rose obviously and the central airway resistance rose in some of them,but the peripheral reactance descended significantly at the same time(P<0.05).There were characteristic changes of IOS in COPD.Conclusions:Using IOS to measure lung function can reflect the variation of airway resistance,espicially the small airway resistance and the lung compliance,which is of value for the diagnosis of COPD.

关 键 词：肺疾病 阻塞性 脉冲振荡法 肺功能 呼吸阻抗 

分 类 号：R563.9[医药卫生—呼吸系统]