脉压差与急性心肌梗死患者心功能相关性分析  

Correlation between pulse pressure and cardiac function of patients with acute myocardial infarction

作　　者：王归真[1] 郭文怡[2] 朱晓惠[1] 

机构地区：[1]西安市第四医院心内科,陕西西安710004 [2]第四军医大学西京医院心内科,陕西西安710033

出　　处：《第四军医大学学报》2005年第1期35-37,共3页Journal of the Fourth Military Medical University

摘　　要：目的 :探讨急性心肌梗死 (AMI)患者脉压差 (PP)与心功能的关系 .方法 :14 1例AMI患者按入院时PP大小分为2组 :A组PP小于 4 .0～ 5 .3kPa (30～ 4 0mmHg) 70例 ;B组PP大于 6 .6～ 8.0kPa (5 0～ 6 0mmHg) 71例 ,回顾性分析两组在年龄、心功能、心率、血脂、性别、收缩压及舒张压的差别 .结果 :与PP小组相比 ,PP大组平均年龄大 [(6 8.7± 12 .2 )岁vs (6 2 .6± 12 .2 )岁 ],心功能差 [(2 .0± 0 .8)级vs (1.7± 0 .8)级 ],收缩压高 [(17.8± 1.9)kPavs (14 .4± 2 .0 )kPa],舒张压高 [(10 .6± 1.8)kPavs(9.8± 1.9)kPa],载脂蛋白B(apoB)高 [(0 .86±0 .2 )mg/Lvs (0 .72± 0 .2 )mg/L],P <0 .0 5～P <0 .0 1,两组之间有高度显著性差异 ;女性比例高 (35 .2 %vs17.1% ) ,低密度脂蛋白胆固醇 (LDL C) [(2 .76± 0 .8)mmol/Lvs (2 .4 9± 0 .5 )mmol/L]、高密度脂蛋白胆固醇 (HDL C) [(1.31± 0 .4 )mmol/Lvs (1.15± 0 .5 )mmol/L]和载脂蛋白A(apoA)高 [(1.10± 0 .4 )mg/Lvs (0 .97± 0 .2 )mg/L],P均 <0 .0 5 ,两组之间有显著性差异 ;而心率 [(82 .3± 19.8)次 /minvs (78.0± 2 0 .1)次 /min],P >0 .0 5 ,两组之间无显著性差异 .结论 :在PP大组的AMI患者年龄大 ,心功能差 ,女性多 ,血脂紊乱多 。AIM: To investigate the correlation between cardiac function and pulse pressure (PP) in patients with acute myocardial infarction (AMI). METHODS: One hundred and forty-one patients were divided into two groups: (A): Lower pulse pressure 4.0-5.3 kPa (30-40 mmHg) group (n=70), and (B): Higher pulse pressure 6.6-8.0 kPa (50-60 mmHg) group (n=71). The differences in age, heart function, heart rate, serum lipid, systolic blood pressure and diastolic blood pressure between the two groups were compared. RESULTS: The age [(68.7± 12.2) year vs (62.6±12.2) year], systolic blood pressure [(17.8±1.9) kPa vs (14.4±2.0) kPa], diastolic blood pressure [(10.6±1.8) kPa vs (9.8±1.9) kPa] and apolipoprotein B (apo B) [(0.86±0.2) mg/L vs (0.72±0.2) mg/L] were higher, and the cardiac function [(2.0±0.8) level vs (1.7±0.8) level] was worse in patients with higher pulse pressure group than those in patients with lower pulse pressure (P<0.05-P<0.01). Compared with those with lower pulse pressure, Female’s proportion (35.2% vs 17.1%) , low-density lipoprotein cholesterol (LDL-C) [(2.76± 0.8) mmol/L vs (2.49±0.5) mmol/L], high-density lipoprotein cholesterol (HDL-C) [(1.31± 0.4) mmol/L vs (1.15±0.5) mmol/L] and apolipoprotein A (apo A) [(1.10±0.4) mg/L vs (0.97±0.2) mg/L] was higher in patients with higher pulse pressure (P all< 0.05) . No difference was found in heart rate [(82.3± 19.8) beat/min vs (78.0±20.1) beat/min] between the two groups (P>0.05). CONCLUSION: The AMI patients with higher pulse pressure tend to be elders, have worse cardiac function and higher blood pressure.

关 键 词：急性心肌梗死 血压 脉压差 心功能 

分 类 号：R542.22[医药卫生—心血管疾病]