颈动脉粥样硬化与冠心病远期心脏事件的关系探讨  

Study on Relationship Between Carotid Atherosclerosis and Cardiac Events in Patients with Coronary Artery Disease

作　　者：徐欣[1] 郑义通[1] 徐默玲[1] 杨承健[1] 胡世文[1] 曹佳宁[1] 杨政杰[1] 黄伟[1] 陈骅[1] 刘凤娥[1] 

机构地区：[1]江苏省无锡市第二人民医院,214000

出　　处：《中国微循环》2004年第6期381-383,共3页Journal of Chinese Microcirculation

摘　　要：目的探讨超声检测颈动脉粥样硬化与冠心病远期心脏事件的相关性。方法将233名疑似冠心病、心肌梗死患者行选择性冠状动脉造影、高分辨率的颈动脉超声检查 ,根据超声检测颈动脉粥样硬化的改变分组列出患者的一般临床资料 ,选择性冠状动脉造影、心电图、超声心动图、平板运动试验的结果等 ,同时随访其心脏事件发生情况。分析超声检测颈动脉粥样硬化与冠心病心脏事件发生情况的相关性。结果233例患者有140例颈动脉超声阳性即颈动脉内中膜厚度(IMT)≥0.8mm(60.1% ) ,233例中221例有随访结果,随访率为94.8% ,随访时间为(21.29±6.26)月 ,有26例患者发生28件心脏事件 ,其发生与体重指数、不稳定性心绞痛、冠脉造影阳性、冠脉造影二支病变、冠脉造影三支病变、颈动脉超声阳性、颈动脉斑块正相关 ,关系密切 (P<0.05) ;多因素非条件Logistic回归分析排除混杂因素影响 ,显示颈动脉超声阳性与颈动脉超声阴性患者的心脏事件有统计学差异(P<0.05)。结论颈动脉超声检测颈动脉粥样硬化可作为预测冠心病心脏事件的独立危险因子。Objective To investigate the relationship between carotid arterosclerosis and cardiac events in patients with coronary artery disease.Methods233patients with suspected coronary heart disease underwent anˉgiography.Carotids were checked by high resolution B-mode ultrasound.Relationship in carotid artherosclerosis,coronary artery disease and the risk factors of coronary artery disease,cardiac events were analysed.Results140of233patients(60.1%)had positive findings with carotid intima_media thickness(IMT)≥0.8mm,221patients were followed.26patients suffered from28cardiac events.There were positive correlations among body mass inˉdex,unstable angina,positive findings in angiography,two_vessel disease,three_vessel disease and carotid plagues(P<0.05).Multiple_factor and non_condition logistic regression,excluding influence of promiscuous factors showed statistic differences between carotid ultrasound and cardiac events(P<0.05).Conclusions Carotid atherosclerosis could be regarded as an independent risk factor in predicting cardiac event in patients with coronary heart disease.

关 键 词：冠心病 颈动脉超声 心脏事件 

分 类 号：R541.4[医药卫生—心血管疾病]