小鼠微核试验检测大气颗粒物致突变性  

Mutagenicity of Total Suspended Particulate in Air by Micronucleus Test in Mice

作　　者：姚加钦[1] 赵贤四[1] 朱惠刚[1] 

机构地区：[1]上海医科大学

出　　处：《上海环境科学》1993年第3期18-20,共3页Shanghai Environmental Sciences

摘　　要：以小鼠微核试验检测上海市有代表性的13个点大气颗粒物的致突变活性,结果表明,上海市大气颗粒物有机提取物能引起小鼠骨髓嗜多染红细胞微核率的升高,且有剂量-反应关系,而各采样点的致微核作用相似.The mutagenicity of total suspended particulate (TSP)in air was detected by micronucleus test in mice was pre sented. By studying thirteen TSP samples of representative of Shanghai. the result showed that the extracts of TSP could increase the frequencies of micronucleated poly chromatic erythrocytes in bone marrow of mice. and there were dose-response relationship but no differences among those samples.

关 键 词：大气 颗粒物 致突变 微核 毒性 

分 类 号：R994.6[医药卫生—毒理学]