医用无菌骨蜡的生物相容性和骨创面止血的疗效评价  

Evaluation on Biological Compatibility and Hemostatic Effect of Sterilized Medical Bone Wax on Bone Wound

作　　者：郭涛[1] 党大胜[1] 宋洪涛[1] 马洪升[1] 牟平[1] 蔡朝红[1] 刘涛[1] 高声传[1] 

机构地区：[1]沈阳军区总医院药剂科,沈阳市110016

出　　处：《中国药房》2005年第1期24-26,共3页China Pharmacy

摘　　要：目的 :评价医用无菌骨蜡的生物相容性及临床疗效。方法 :以家兔为实验对象分别进行植入实验、病理实验和溶血实验 ;调查12531例/次病例的疗效及愈后率。结果 :植入的骨蜡不被吸收 ,被结缔组织包裹 ,周围无水肿、炎症和坏死 ;病理观察见松质骨断面止血后骨蜡不被吸收 ;无溶血现象发生 ,临床止血效果理想 ,甲级愈合率达99 1%。结论 :医用无菌骨蜡生物相容性良好 ,独立灭菌包装取用方便 ,止血安全、可靠。OBJECTIVE:To evaluate the biological compatibility and clinical therapeutic effect of the medical sterilized bone wax.METHODS:Embedding test and pathological test as well as hemolytic test were performed by using rabbits as test animal.12531case-times were investigated in respect to the therapeutic effect,prognosis and satisfactory rate.RESULTS:The embedded bone wax was coated by connective tissue and has not been absorbed without surrounding inflammation,edema or necrosis.The bone wax could not be absorbed after stanching bleeding of the bone broken surface.No hemolytic phenomena were observed.The wound healing obtained a satisfactory rate of99.1%.CONCLUSION:The sterilized medical bone wax has good biological compatibility and is safe and effective to stanch bleeding.It is convenient to use due to its singer dose sterilized packaging.

关 键 词：医用无菌骨蜡 生物相容性 临床应用 骨创面止血 

分 类 号：R973.1[医药卫生—药品]