单纯结核性渗出性胸膜炎6月短程化疗的疗效分析  

The clinical outcome of 6-month short-course chemotherapy on pure effusive tuberculous pleurisy

作　　者：罗萍[1] 潘欣[1] 屠德华[1] 

机构地区：[1]北京结核病控制研究所,北京100035

出　　处：《中国防痨杂志》2005年第1期5-7,共3页Chinese Journal of Antituberculosis

摘　　要：目的　了解初治单纯结核性渗出性胸膜炎 6月短程化疗效果 ,并探讨疗程。方法　回顾分析北京市 1 996— 2 0 0 0年 9个区县结核病防治所符合选例标准的 2 5 6例单纯结核性渗出性胸膜炎 6月短程化疗的近、远期疗效。结果　治疗 6月末胸液完全吸收率为 73.0 %(1 87/2 5 6 ) ;随访 4 8月 ,2例复发 ,复发率 1 .4 %(2 /1 39)。未完全吸收病例继续化疗至 9～ 1 2月 ,4 8月复发 2例 ,复发率 2 .2 %(2 /92 )。有症状至就诊时间 2 8d和 >2 8d病例 6月胸液明显吸收率分别为 87.1 %(1 96 /2 2 5 )和6 7.7%(2 1 /31 )。无明显胸膜增厚率分别为 5 4.7%(1 2 3/2 2 5 )和 32 .3%(1 0 /31 ) ,两者有显著性差别。结论　单纯结核性渗出性胸膜炎采用 6月标准短程化疗方案 ,近、远期效果良好 ;对 6月末胸液尚未完全吸收的病人可适当延长疗程至 9～ 1 2月 ;早期诊断、早期治疗有利于胸液吸收和减少胸膜增厚。Objective To determine the therapeutic effect of 6-month short-course chemotherapy of pure effusive tuberculous pleurisy,and to evaluate the period of treatment.Methods 256 cases of new pure effusive tuberculous pleurisy diagnosed and treated from 1996 to 2000 in 9 counties (distriats) TB Dispensaries in Beijing were reviewed and analyzed retrospectively.Results The rate of pleural effusion absorbed completely was 73.0% (187/256) at the end of 6-month.The cases were followed up 48 months and the relapse rate was 1.4%(2/139).The cases of pleural effusion not absorbed entirely continue received their treatment to 9～12 months,the relapse rate of following up 48 months was 2.2% (2/92).The patients with the duration between illness and clinical consultation ≤28 days or >28 days,the rate of pleural effusion absorbed evidently were 87.1%(196/225)、67.7%(21/31) respectively at the end of 6-month.The rate of pleural not thickening were 54.7%(123/225)、32.3%(10/31) respectively,both rates were statistically significantly different.Conclusion The outcome of pure effusive tuberculous pleurisy used 6-month,the patients of pleural effusion not absorbed entirely could take their chemotherapy to 9～12 months.The early diagnosis and treatment were of benefit to the absorbing of pleural effusion and the reduction of pleural thickening.

关 键 词：结核性渗出性胸膜炎 胸液 短程化疗 胸膜增厚 复发率 疗效分析 治疗 结论 显著性 北京 

分 类 号：R521.7[医药卫生—内科学]