HRP法对几丁质桥接周围神经缺损的评价  

AN HRP ASSESSMEN OF THE CHITIN BRIDGE IN PERIPHERAL NERVE REPAIR

作　　者：苟三怀[1] 侯春林[1] 周世臣[2] 

机构地区：[1]第二军医大学附属长征医院骨科 [2]第二军医大学解剖教研室

出　　处：《上海医学》1993年第3期130-132,2,共3页Shanghai Medical Journal

摘　　要：作者首次应用几丁质作为一种新型生物材料桥接大白鼠坐骨神经缺损的实验研究,采用HRP 逆行示踪法对桥接术后8周大白鼠进行了鉴定,结果表明,几丁质桥接的大白鼠坐骨神经缺损在术后8周近侧端的再生神经纤维通过几丁质再生室长入远端的神经干中,比肌桥提前了4周。In the experimental study,a segment of 6em in length of rat's sciatic nerve was inc- ised and then bridged chitin and skeletal muscles,8 weeks after the operation the HRP- labeled cells were observed in the front horn of the lumbar spinal cord.The results appa- rently indicate that the proximal end of the severed sciatic nerve has been regenerated through chambers and reached to the distal nerve trunk within 8 week savter the operation.

关 键 词：几丁质 坐骨神经缺损 神经再生 HRP 

分 类 号：R318.08[医药卫生—生物医学工程]