玻璃体内注射清栓酶治疗实验性玻璃体积血  

INTERAVITREAL SVATE TREATEMENT OF EXPERIMENTAL VITREOUS HEMORRHAGE

作　　者：陈梅珠[1] 周国筠 

机构地区：[1]广州第一军医大学南方医院眼科,510515

出　　处：《蛇志》1993年第2期2-5,共4页Journal of Snake

摘　　要：清栓酶可促进玻璃体内纤维蛋白凝血块溶解,我们制作新鲜及陈旧性兔眼玻璃体积血模型,将清栓酶、尿激酶及注射用水分别注入玻璃体腔内,观察眼底、测定玻璃体出血指数、FDP含量、进行3P 试验,结果发现清栓酶有治疗效果,同对照组相比统计学上有显著差异,同尿激酶相比无差异,且未发现有毒副作用。Svate can promote rapid resolution of intraocular fibrin clots.We produced fresh and old models of vitreous hemorrhage.The efficacy of intravitrcal svate in promoting the shortterm clear- anec of vitreous hemorrhage was investigated by ophthahnoscopy,vitreous hemorrhage index, vitreous concentration of fibrin(ogcn)degradation product(FDP)and 3P experiment.Three treat- ment groups of Svate,Urokinase and control were studied.The Svate and UK group showed a statistically significant difference as compared with control group,respectively.However,there was no statistical difference in Svate and,UK group.No evidence of toxicity was observed in Svate group.

关 键 词：清栓酶 尿激素 玻璃体积血 疗效 

分 类 号：R977.3[医药卫生—药品]