视觉细胞反应中方向选择性和取向选择性成分的分离  

SEPARATION OF THE DIRECTIONAL COMPONENT FROM ORIENTATIONAL COMPONENT IN THE VISUAL NEURONS RESPONSE

作　　者：李兵[1] 王毅[1] 刁云程[1] 

机构地区：[1]中国科学院生物物理研究所视觉信息加工开放研究实验室,北京100101

出　　处：《生物物理学报》1993年第1期86-94,共9页Acta Biophysica Sinica

基　　金：国家自然科学基金

摘　　要：运动的光刺激常被用于研究视觉神经细胞的方向和取向选择性.但是,在细胞的反应中,两种因素同时存在且混杂在一起; 以往的各种分析方法均因未能有效地解决这一问题而不够准确,对此我们给出了理论和实例证明.本工作引入正余弦函数系对实验数据作最优回归分析.拟合程度好于以往的方法.并且从根本上分离了反应中的方向和取向选择性成分.使对这两种性质的准确定量成为可能.本文对此方法的内在含义作出了解释,并提出了对方向、取向选择性及最优方向、取向的理解.Moving optical stimuli are extensively used in studies of the directional and or orientational selectivities of visual neurons. However, since these two components usually coexist and are mixed in the cell's overall responses, it is desired to separate them from each other for analysis. In this paper, we provide theoretical evidence and some examples to show that the previous data analysis methods could not resolve this problem effectively. consequently the results were not precise enough. We propose to use the sine cosine function series as the fundamental variables and to apply optimum regression analysis to the experimental data. The results fit original data much better than results obtained using the previous methods. the directional and orientational components are separated completely, and it is possible to quantitatively determine these two properties precisely. Further more, we give an explanation of the intrinsic implication of the present method and our comprehension about directional orientational selectivity and preferred direction orientation.

关 键 词：视觉反应 取向选择性 方向选择性 

分 类 号：Q811.4[生物学—生物工程]