特发性血小板减少性紫癜患儿血清白细胞介素-4、-6、-8变化  

Detection of Interleukin-4,-6,-8 in Children with Idiopathic Thronbocytopenic Purpura

作　　者：张树人[1] 冯建飞[1] 盛光耀[2] 

机构地区：[1]郑州大学第三附属医院儿科 [2]郑州大学第一附属医院,郑州450052

出　　处：《实用儿科临床杂志》2005年第1期26-27,共2页Journal of Applied Clinical Pediatrics

摘　　要：目的　探讨特发性血小板减少性紫癜 (ITP)患儿血清白细胞介素 (IL)的变化。方法　应用ELISA法测定ITP 35例患儿和正常儿童 2 0例血清IL 4、 6、 8含量。结果　ITP患儿血清IL 4、6、8均高于正常儿童 ,两组比较有显著性差异 (t=2 .2 4 2　P <0 .0 5 ;t=3 .0 91　P <0 .0 1 ;t=3 .452　P <0 .0 1 )。结论　IL参与ITP的发病过程。Objective To study the changes of interleukin-4(IL-4),IL-6,IL-8 in children with idiopathic thrombocytopenic purpura(ITP).Methods The serum of IL-4,IL-6,IL-8 in 35 ITP patients and 20 normal control children were detected by enzyme-linked immunosorbent assay.Results The serum IL-4,IL-6,IL-8 in ITP patients were elevated. There were significant difference between ITP group and control group(P<0.05,P<0.01,P<0.01, respectively).Conclusion Interleukin maybe take part in the etiology of ITP.

关 键 词：紫癜 血小板减少性 特发性 白细胞介素-4 白细胞介素-6 白细胞介素-8 酶联免疫吸附法 

分 类 号：R725.5[医药卫生—儿科]