不同来源的精子显微受精治疗男性不育  

The impact of the source of spermatozoa used for intracytoplasmic sperm injection in treating different male infertility

作　　者：张文香[1] 曹云霞[1] 周平[1] 章志国[1] 赵济华[1] 

机构地区：[1]安徽医科大学第一附属医院妇产科生殖中心,合肥230022

出　　处：《安徽医科大学学报》2004年第6期468-470,共3页Acta Universitatis Medicinalis Anhui

摘　　要：目的　回顾分析不同来源精子的单精子卵胞浆内注射 (ICSI)治疗男性不育 6 2个周期。方法　比较采用手淫射精获得精子、睾丸活切及附睾穿刺获得精子行ICSI治疗后的受精率、卵裂率、优质胚胎率及临床妊娠率。结果　射出精子组 5 0个周期 ,受精率 72 3%、卵裂率 80 %、优质胚胎率4 0 %及临床妊娠率 4 0 % ;睾丸及附睾精子组 12个周期 ,受精率 6 4 1%、卵裂率 76 3%、优质胚胎率 35 2 %及临床妊娠率 33 3%。两组结果比较 ,无显著性差异。结论　不同来源精子行ICSI治疗男性因素不育可以获得相似的治疗结果。Objective The aim of this retrospective study was to find out whether the source of sperm has an impact on the outcome of ICSI.Methods The mature oocytes were microinjected with sperm from ejaculates,epididymal aspirates and testicular sperm. The oocyte fertilization,embryo cleavage,good qulity embryo and clinical pregnancy rates were evaluated and compared.Results In the ejaculation group(n=50),the fertilization rate was 72.3%; and the cleavage rate, 80%;the good quality embryo rate, 40% and the clinical pregnancy rate, 40%.In the epididymal aspirates and testicular group(n=12),fertilization,cleavage,good quality embryo and the clinical pregnancy rate was 64.1%,76.3%,35.2% and 33.3% respectively.There were not significant difference between the two groups.Conclusion The ejaculated,epididymal aspirates and testicular sperm used in ICSI achieved comparable clinical results.

关 键 词：单精子胞浆内注射技术 不育 男性 精子 

分 类 号：R711.6[医药卫生—妇产科学]