103例流行性出血热患者的心电图及心肌酶学分析  

Analysis on the Electrocardiogram and Myocardium Enzymology of 103 Cases with Epidemic Hemorrhagic Fever(EHF)

作　　者：唐正运[1] 叶晓光[1] 李石好[1] 廖云珍[1] 

机构地区：[1]广州医学院附属第二医院感染病科,广州510260

出　　处：《热带医学杂志》2004年第6期723-725,共3页Journal of Tropical Medicine

摘　　要：目的了解流行性出血热病毒(EHFV)对心脏的损害情况。方法对103例流行性出血热(EHF)患者的心电图及心肌酶学检测结果进行分析。结果72例(69.9%)患者出现心电图异常,以窦性心动过缓(27.9%)及窦性心动过速(22.3%)最常见,明显高于其它类型的心电图改变(P分别<0.05和0.001)。103例流行性出血热(EHF)患者的CK、LDH及HBDH的升高者分别为43例(41.2%)、73例(70.9%)及46例(44.7%),以LDH异常最常见。轻型、中型、重型及危重型流行性出血热患者的LDH值分别为(346.3±155.6)IU/L、(330.7±130.7)IU/L、(1114.4±872.4)IU/L及(1227.1±936.7)IU/L,经统计学处理重型及危重型的值与轻型、中型比较均有显著性或高度显者性差异。结论EHF患者并发心肌损害较普遍,而且病情愈重者,心肌损害愈严重。Objective To investigate the heart lesion caused by epidemic hemorrhagic fever virus (EHFV). Method A restrospective analysis on the electrocardiogram and myocardium enzymology of 103 cases with epidemic hemorrhagic fever were carried out.Results There were 72 cases (69.9%) with abnormal electrocardiogram. Sinus bradycardia (27.9%) and sinus tachycardia (22.3%) were the most common abnormal features and significantly higher than the other abnormal (P< 0.05 and 0.01, respectively).Elevation in CK was 43 cases (41.2%), in LDH was 73 cases (70.9%) and in HBDH was 46 cases (44.7%). So the abnormal increase in LDH level was a common feature. LDH of patients with mild, moderate, severe and critical conditions were (346.3±155.6)IU/L, (330.7±130.7)IU /L, (1 114.4±872.4)IU /L and (1 227.1 ±936.7)IU /L, respectively. The LDH levels of patients in severe and critical condition were dramatically and significantly higher than that in mild and moderate condition. Conclusions The complicated myocardial lesion is commonly observed in the patients with EHF. The more severe the disease is, the more severe is the lesion.

关 键 词：流行性出血热 并发症 心肌损害 

分 类 号：R373.32[医药卫生—病原生物学]