组织工程皮肤的缺陷与对策  

Shortcomings and countermeasures of the tissue engineered skin

作　　者：陆新[1] 韩春茂[2] 

机构地区：[1]解放军第一一七医院烧伤整形科,浙江杭州310013 [2]浙江大学医学院附属二院烧伤科,浙江杭州310009

出　　处：《医学研究生学报》2005年第1期74-76,共3页Journal of Medical Postgraduates

摘　　要：组织工程皮肤的研究发展迅速 ,但至今仍无一种理想的皮肤替代物 ,主要的缺陷是容易感染、移植成功率低、缺乏皮肤附属器 ,保存方法不完善 ,免疫排斥问题没有完全解决。目前的对策有 :加入抗生素或应用有抗感染能力的材料 ,促进组织工程皮肤血管化 ,初步构成含毛囊的组织工程皮肤 ,尝试冷冻保存及减低移植物抗原性。Researches on tissue engineered skin develops quickly, there is no ideal skin substitutes by now. The main shortcomings are easy to be infected, low take rate, without skin appendage, no good preservation method and no perfect solution to immune rejection problem. The countermeasures by now are adding antibiotics to the tissue engineered skin or using materials with anti infection ability, promoting angiogenesis, constructing tissue engineered skin with hair fonicles, tryig to cryopreserve the tissue engineered skin and decreasing antigenicity.

关 键 词：组织工程 皮肤 缺陷 对策 

分 类 号：R318.19[医药卫生—生物医学工程]