pH值对化学沉淀法制备纳米羟基磷灰石的影响  

Effect of pH Value on Nanosized Hydroxyapatite Synthesized through Precipitation Process

作　　者：王德平[1] 王璐[1] 黄文旵[1] 

机构地区：[1]同济大学材料科学与工程学院,上海200092

出　　处：《同济大学学报（自然科学版）》2005年第1期93-98,共6页Journal of Tongji University:Natural Science

基　　金：上海市纳米专项基金资助项目 (0 14 4nm0 64 )

摘　　要：介绍了以硝酸钙乙醇溶液和磷酸氢二氨水溶液为前驱体 ,用化学沉淀法制备纳米羟基磷灰石粉体的工艺方法 .借助X射线衍射 (XRD)、红外吸收光谱 (IR)、差热分析 (DTA)、激光粒度分析 (LSPSA)和透射电镜 (TEM)等测试手段对样品的结晶相、组成、形貌等进行了观察分析 ,着重讨论了制备工艺中 pH值对样品性能产生的重要影响 .结果表明 ,随着溶液pH值的增高 ,样品的组成和结晶度呈现出明显的变化 .在水浴 1 5℃、溶液 pH =1 0 .5、陈化 1 4h后可制得结晶较好、组分单一、尺寸在 30nm左右的纳米羟基磷灰石粉体 .The techniques of synthesizing nanoscale hydroxyapatite (Ca 10(PO 4) 6(OH) 2 or HA) powder by precipitation process,using Ca(NO 3) 2 dissolved in anhydrous ethanol and (NH 4) 2HPO 4 dissolved in distilled water as precursors,was discussed in detial.X-ray diffraction(XRD),infrared spectroscopy(IR),differential thermal analysis(DTA),laser particle size analysis (LSPSA) and transmission electron microscope(TEM) were used to characterize the crytal phase,chemical composition and morphology of nanoscale hydroxyapatite (HA) powder.Great focus was put on the study about the remarkable influence of pH value on the characteristics of HA powder.The result showed that the composition and the crystal formation of the samples varied obviously according to different pH values,and when the temperature of solution was at 15 ℃,with pH=10.5,the particle size of HA was observed to be very fine,uniform,and around 30 nm,after aging for 14 h.

关 键 词：纳米羟基磷灰石 化学沉淀法 PH值 

分 类 号：R318.08[医药卫生—生物医学工程] TQ174.758[医药卫生—基础医学]